Functional GI & Motility

05
Track 05 of 9

Functional GI & Motility

IBS, gastroparesis and neurogastroenterology.

Disorders of gut-brain interaction are being reframed by Rome IV, high-resolution manometry, and the wireless motility capsule. IBS-D management now integrates eluxadoline, rifaximin re-treatment, and low-FODMAP diets, while linaclotide, plecanatide, and tenapanor anchor IBS-C care. EndoFLIP and HRM with the Chicago Classification 4.0 differentiate achalasia subtypes and EGJ outflow obstruction. Gastroparesis sees renewed interest in prucalopride, ghrelin agonists (relamorelin), and gastric peroral endoscopic myotomy (G-POEM). Sessions also cover cyclic vomiting syndrome, rumination, and the central neuromodulator class for visceral hypersensitivity.

Focus areas
  • IBS-D: eluxadoline, rifaximin and low-FODMAP evidence
  • IBS-C: linaclotide, plecanatide, tenapanor mechanisms and outcomes
  • Achalasia subtyping: HRM Chicago Classification 4.0 and EndoFLIP
  • Gastroparesis: prucalopride, relamorelin and G-POEM outcomes
  • GERD long-term PPI safety and vonoprazan as PCAB alternative
  • Central neuromodulators in DGBI: TCAs, SNRIs, atypical agents
  • Cyclic vomiting and cannabinoid hyperemesis syndrome